On July 8, 2025, the teams led by Professor Han Jianfeng and Professor Yu Jia from Department of Neurology of the First Affiliated Hospital (FAH) of Xi'an Jiaotong University (XJTU) successfully applied YONFLOW blood flow guiding device for an intracranial aneurysm patient for the first time in the northwest region, indicating that the neurointerventional team from Department of Neurology of FAH occupied the forefront in China and the leading position in the northwest in the interventional treatment of intracranial aneurysm.

A 67-year-old male patient received conservative treatment for cerebral infarction due to weakness of the left limb in a local hospital. After relevant symptoms were mitigated, he was admitted to FAH to further identify the cause of cerebral infarction. Cranial DSA detected an aneurysm, approximately 4.33×4.4 mm in size, on the left internal carotid artery. After fully informing surgical necessity and risks, the patient and his family decided to undergo the surgery.

Upon admission, comprehensive preoperative examination, careful preoperative discussion and drug preparation were carried out. With tremendous supports from Department of Anesthesiology and Perioperative Medicine and Interventional Operating Room, Professor Han Jianfeng and Professor Yu Jia led team members to successfully perform angioplasty using YONFLOW blood flow guiding device. The stent adhered well to vascular wall. Postoperatively, the patient was transferred to ICU of Department of Neurology for close observation, and returned to general ward the next day. He has been discharged after recovery.

The principle of treating intracranial aneurysms with flow-guiding dense mesh stent is as follows: through the design of high metal coverage and high mesh rate of the flow-guiding dense mesh stent, the local blood flow can be reshaped. The impact blood flow from the parent artery into the aneurysm is directed into the distal normal blood vessels, thereby reducing the impact of local blood flow on the aneurysm, improving the hemodynamic status within the aneurysm, finally forming a thrombus in the aneurysm, thus realizing the occlusion of the aneurysm. The advent of dense mesh stent has brought novel ideas and methods for endovascular treatment of complex aneurysms. As the world's first 100% recyclable dense mesh stent, YONFLOW dense mesh stent can be completely pushed out and then recycled into the micro-catheter, which is completely controllable. It increases the safety and precision for the surgeons. The distal end of the stent is designed as a spherical head end, which reduces stent delivery resistance and alleviates vascular injury. It is made of cobalt-chromium alloy, which ensures strong radial support and close vascular adhesion. It has shown high safety and effectiveness in clinical application.